Differin is a gel that is used in the treatment of moderate to severe acne. It contains the active ingredients adapalene.
Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.
Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.
Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.
Do not apply to broken skin.